Description

Job Description

The Tortelote Lab at Tulane University School of Medicine, Department of Pediatrics, is seeking an outstanding candidate for a post-doctoral position. A postdoctoral position is available in a dynamic research laboratory at Tulane University investigating the molecular and metabolic mechanisms that regulate kidney development.

Our laboratory studies how cellular metabolism regulates the molecular and epigenetic mechanisms that shape kidney development, with a particular focus on nephron progenitor (stem cell) fate decisions and nephron formation. We combine mouse genetics, single-cell and multi-omics profiling, and advanced cellular and imaging approaches to investigate how metabolic pathways and inter-organelle communication influence progenitor cell maintenance, differentiation, and nephrogenesis. A major goal of our work is to understand how early-life insults, such as nutritional imbalances, reprogram kidney development and predispose individuals to kidney disease across multiple generations. Notably, our lab has developed metabolic intervention strategies aimed at restoring normal developmental trajectories.

The postdoc scientist will focus on how metabolic signaling and inter-organelle communication regulate nephron progenitor cell fate and whether metabolic interventions can restore normal kidney development following early-life nutritional stress.

The successful candidate will contribute to ongoing projects examining molecular, metabolic, and epigenetic pathways that regulate stem cell fate and developmental processes using mouse models and integrative molecular approaches.

Research Environment:

Tulane University offers a highly collaborative research environment with access to state-of-the-art genomics, metabolomics, and imaging core facilities that support innovative biomedical research. The successful candidate will be encouraged to develop independent research directions, participate in grant and fellowship applications, and receive mentorship aimed at supporting the transition to an independent research career.

Appointment:

The appointment is reviewed annually and renewable for up to three years, contingent upon research performance and funding availability.

Required Applicant Materials:

Interested candidates should submit the following materials:

• Curriculum Vitae
• Brief statement of research interests
• Contact information for at least three professional references

For further inquiries about this position, please email Dr. Giovane Tortelote, at gtortelote@tulane.edu

Responsibilities

Responsibilities:

The successful candidate will:

• Design and conduct independent research projects under the guidance of the Principal Investigator
• Analyze and interpret experimental data
• Contribute to manuscript preparation and presentation of research findings
• Collaborate effectively within a multidisciplinary research environment

Qualifications

Required Qualifications:

Applicants must hold a Ph.D. in Cell Biology, Developmental Biology, Biochemistry, Genetics, or a related field.

Candidates should demonstrate:

• A strong publication record and evidence of research productivity
• The ability to design, execute, and interpret independent experiments
• Excellent written and oral communication skills

Preferred Technical Skills

• Experience in one or more of the following areas is highly desirable:
• Mammalian cell and tissue culture
• Mouse handling and colony management
• Cre/loxP genetic approaches for tissue-specific gene manipulation

Experience with molecular biology and biochemistry techniques (qPCR, genotyping, western blotting, immunostaining, fluorescence or confocal imaging) and experience with cellular metabolism analysis, single-cell genomics, or multi-omics approaches are a plus.

About Us

Tulane University is an equal opportunity educator and employer committed to providing an education and employment environment free of unlawful discrimination, harassment, and retaliation. Legally protected demographic classifications (such as a person's race, color, religion, age, sex, national origin, shared ancestry, disability, genetics, veteran status, or any other characteristic protected by federal, state, or local laws) are not relied upon as an eligibility, selection or participation criteria for Tulane's employment or educational programs or activities.

Tulane University is responsible for providing reasonable accommodations to individuals with disabilities throughout the applicant screening process. If you need assistance in completing an application or during any phase of the interview process, please contact the Office of Human Resources by phone at 504-865-4748 or by email at [email protected].